In-situ biophysical characterization of high-concentration protein formulations using wNMR

• Main Authors: Jing Song (Author), Marc Taraban (Author), Y. Bruce Yu (Author), Lynn Lu (Author), Pallavi Guha Biswas (Author), Wei Xu (Author), Hanmi Xi (Author), Akhilesh Bhambhani (Author), Guangli Hu (Author), Yongchao Su (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACTHigh-concentration protein formulation is of paramount importance in patient-centric drug product development, but it also presents challenges due to the potential for enhanced aggregation and increased viscosity. The analysis of critical quality attributes often necessitates the transfer of...