Manufacturability and functionality assessment of different formats of T-cell engaging bispecific antibodies

• Main Authors: Han Ping Loh (Author), Farouq Bin Mahfut (Author), Serene W Chen (Author), Yuhan Huang (Author), Jianxin Huo (Author), Wei Zhang (Author), Kong Peng Lam (Author), Shengli Xu (Author), Yuansheng Yang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACTT-cell-engaging bispecific antibodies (T-bsAbs) are promising immunotherapies for cancer treatment due to their capability of redirecting T-cells toward destroying tumor cells. Numerous T-bsAb formats have been developed, each with advantages and disadvantages in terms of developability, imm...