SERCA inhibition improves lifespan and healthspan in a chemical model of Parkinson disease in Caenorhabditis elegans

SERCA inhibition improves lifespan and healthspan in a chemical model of Parkinson disease in Caenorhabditis elegans

Introduction: The high prevalence of neurodegenerative diseases in our population and the lack of effective treatments encourage the search for new therapeutic targets for these pathologies. We have recently described that submaximal inhibition of the Sarco-Endoplasmic Reticulum Ca2+ ATPase (SERCA),...

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Main Authors: Silvia Romero-Sanz (Author), Elena Caldero-Escudero (Author), Pilar Álvarez-Illera (Author), Jaime Santo-Domingo (Author), Rosalba I. Fonteriz (Author), Mayte Montero (Author), Javier Álvarez (Author)
Format: Book
Published: Frontiers Media S.A., 2023-05-01T00:00:00Z.
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