Anti-Colorectal Cancer Effects of a Novel Camptothecin Derivative PCC0208037 <i>In Vitro</i> and <i>In Vivo</i>

• Main Authors: Min Li (Author), Linxu Wang (Author), Yingjie Wei (Author), Wenyan Wang (Author), Zongliang Liu (Author), Aixia Zuo (Author), Wanhui Liu (Author), Jingwei Tian (Author), Hongbo Wang (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Colorectal cancer is one of the most common malignancies, and the topoisomerase inhibitor irinotecan (CPT-11)-based chemotherapeutic regimen is currently the first-line treatment with impressive therapeutic efficacy. However, irinotecan has several clinically significant side effects, including diar...