A Severe Case of Cutaneous Adverse Drug Reaction Secondary to a Novice Drug: Idelalisib

• Главные авторы: Joseph Gabriel Gabriel MD (Автор), Aaysha Kapila MD (Автор), Alexei Gonzalez-Estrada MD (Автор)
• Формат: ‌
• Опубликовано: SAGE Publishing, 2017-05-01T00:00:00Z.
• Предметы: article
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Phosphatidylinositol 3-kinase δ (PIK3δ) is a tyrosine kinase essential for B cell survival, making it an important target in the treatment of chronic lymphocytic leukemia. Idelalisib is an inhibitor of PIK3δ demonstrating initial success in disease response, but is now shown to have a decreased over...