Pharmacological characterization of the native store-operated calcium channels of cortical neuronal from embryonic mouse brain

• Main Authors: Sylvain Chauvet (Author), Louis Jarvis (Author), Mireille Chevallet (Author), Niroj Shrestha (Author), Klaus Groschner (Author), Alexandre Bouron (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the murine brain, the first post-mitotic cortical neurons formed during embryogenesis express store-operated channels (SOCs) sensitive to Pyr3, initially proposed as a blocker of transient receptor potential channel of C type 3 (TRPC3 channel). However Pyr3 does not discriminate between Orai and...