Delayed Mitochondrial Membrane Potential Disruption by ATP in Cultured Rat Hippocampal Neurons Exposed to N-Methyl-d-Aspartate

• Main Authors: Koichi Fujikawa (Author), Noritaka Nakamichi (Author), Shunsuke Kato (Author), Ryo Fukumori (Author), Miho Hida (Author), Takeshi Takarada (Author), Yukio Yoneda (Author)
• Format: Book
• Published: Elsevier, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Necrotic damage leads to a massive leakage from injured cells of different intracellular constituents such as glutamate (Glu) and ATP, which are believed to play a role in the neuronal survival in the brain. In this study, we evaluated pharmacological properties of ATP, which is shown to be an endog...