Histidine 19 Residue Is Essential for Cell Internalization of Antifungal Peptide SmAP_α1-21 Derived from the α-Core of the <i>Silybum marianum</i> Defensin DefSm2-D in <i>Fusarium graminearum</i>

• Hauptverfasser: Agustina Fernández (Verfasst von), Mariano González (Verfasst von), Ismael Malbrán (Verfasst von), Romina F. Vázquez (Verfasst von), Sabina M. Maté (Verfasst von), Fanny Guzmán (Verfasst von), Laura S. Bakás (Verfasst von), Sandra Vairo Cavalli (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2022-10-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

The synthetic peptide SmAP_α1-21 (KLCEKPSKTWFGNCGNPRHCG) derived from DefSm2-D defensin α-core is active at micromolar concentrations against the phytopathogenic fungus <i>Fusarium graminearum</i> and has a multistep mechanism of action that includes alteration of t...