Gene Therapy for Systemic or Organ Specific Delivery of Manganese Superoxide Dismutase

• Main Authors: Joel S. Greenberger (Author), Amitava Mukherjee (Author), Michael W. Epperly (Author)
• 格式: 图书
• 出版: MDPI AG, 2021-06-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Manganese superoxide dismutase (MnSOD) is a dominant component of the antioxidant defense system in mammalian cells. Since ionizing irradiation induces profound oxidative stress, it was logical to test the effect of overexpression of MnSOD on radioresistance. This task was accomplished by introducti...