Characterisation of an Isogenic Model of Cisplatin Resistance in Oesophageal Adenocarcinoma Cells

• Main Authors: Amy M. Buckley (Author), Becky AS. Bibby (Author), Margaret R. Dunne (Author), Susan A. Kennedy (Author), Maria B. Davern (Author), Breandán N. Kennedy (Author), Stephen G. Maher (Author), Jacintha O'Sullivan (Author)
• Format: Book
• Published: MDPI AG, 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cisplatin (cis-diamminedichloroplatinum) is widely used for the treatment of solid malignancies; however, the development of chemoresistance hinders the success of this chemotherapeutic in the clinic. This study provides novel insights into the molecular and phenotypic changes in an isogenic oesopha...