GENOTYPE POLYMORPHISMS OF NAT2 AND CYP2E1 GENES ASSOCIATED WITH DRUG INDUCED LIVER INJURY (DILI) IN INDONESIAN TUBERCULOSIS PATIENTS

• Main Authors: Dyah Aryani Perwitasari (Author), Malinda Noverliyanti (Author), Endang Darmawan (Author), Ully Adhi Mulyani (Author), Jarir Atthobari (Author), Bob Wilffert (Author)
• Format: Book
• Published: Universitas Gadjah Mada, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Currently, Indonesia is in the fifth rank of highest TB prevalence over the world. One of the TB problem is low patients' adherence due to the oral antituberculosis induced hepatotoxicity. Polymorphisms of NAT2 and CYP2E1 genes had important role in the isoniazid (INH)-induced hepatotoxicity. T...