Pimpinellin Inhibits Collagen-induced Platelet Aggregation and Activation Through Inhibiting Granule Secretion and PI3K/Akt Pathway

• Hoofdauteurs: Gang Liu (Auteur), Zhaowei Yuan (Auteur), Xiaoyun Tian (Auteur), Xiuqin Xiong (Auteur), Fang Guo (Auteur), Zihan Lin (Auteur), Zhen Qin (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Pimpinellin is a coumarin-like compound extracted from the root of Toddalia asiatica. Its effects on platelet function has not been investigated. This study found that pimpinellin pretreatment effectively inhibited collagen-induced platelet aggregation, but did not alter ADP- and thrombin-induced ag...