Concentration‐QTc and cardiac safety analysis of single and multiple zavegepant nasal spray doses in healthy participants to support approval

Abstract Zavegepant is a novel gepant administered as a nasal spray approved in the United States at a 10 mg dose for the acute treatment of migraine with or without aura in adults. The cardiovascular safety of zavegepant nasal spray was assessed in both single‐ascending dose (SAD) and multiple‐asce...

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Main Authors: Jim H. Hughes (Author), Richard Bertz (Author), Rajinder Bhardwaj (Author), Mary K. Donohue (Author), Jennifer Madonia (Author), Matt S. Anderson (Author), Beth A. Morris (Author), Robert S. Croop (Author), Jing Liu (Author)
Format: Book
Published: Wiley, 2024-06-01T00:00:00Z.
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