Over-Expression of Inhibitor of Differentiation 2 Attenuates Post-Infarct Cardiac Fibrosis Through Inhibition of TGF-β1/Smad3/HIF-1α/IL-11 Signaling Pathway

Background: Cardiac fibrosis after myocardial infarction mainly causes cardiac diastolic and systolic dysfunction, which results in fatal arrhythmias or even sudden death. Id2, a transcriptional repressor, has been shown to play an important role in the development of fibrosis in various organs, but...

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Main Authors: Lin Yin (Author), Ming-xin Liu (Author), Wei Li (Author), Feng-yuan Wang (Author), Yan-hong Tang (Author), Cong-xin Huang (Author)
Format: Book
Published: Frontiers Media S.A., 2019-11-01T00:00:00Z.
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