Automatic evaluation of tumor budding in immunohistochemically stained colorectal carcinomas and correlation to clinical outcome

• Main Authors: Cleo-Aron Weis (Author), Jakob Nikolas Kather (Author), Susanne Melchers (Author), Hanaa Al-ahmdi (Author), Marion J. Pollheimer (Author), Cord Langner (Author), Timo Gaiser (Author)
• Format: Book
• Published: BMC, 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Tumor budding, meaning a detachment of tumor cells at the invasion front of colorectal carcinoma (CRC) into single cells or clusters (<=5 tumor cells), has been shown to correlate to an inferior clinical outcome by several independent studies. Therefore, it has been discussed...