Zein nanoparticles as nontoxic delivery system for maytansine in the treatment of non-small cell lung cancer

• Автори: Xianglong Yu (Автор), Huichao Wu (Автор), Haiyan Hu (Автор), Ziyi Dong (Автор), Yunni Dang (Автор), Qi Qi (Автор), Yan Wang (Автор), Shouying Du (Автор), Yang Lu (Автор)
• Формат: Книга
• Опубліковано: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Purpose Maytansine (DM1) is a potent anticancer drug and limited in clinical application due to its poor water solubility and toxic side effects. Zein is widely used in nano drug delivery systems due to its good biocompatibility. In this study, we prepared DM1-loaded zein nanoparticles (ZNPs) to ach...