Zein nanoparticles as nontoxic delivery system for maytansine in the treatment of non-small cell lung cancer

• Main Authors: Xianglong Yu (Author), Huichao Wu (Author), Haiyan Hu (Author), Ziyi Dong (Author), Yunni Dang (Author), Qi Qi (Author), Yan Wang (Author), Shouying Du (Author), Yang Lu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose Maytansine (DM1) is a potent anticancer drug and limited in clinical application due to its poor water solubility and toxic side effects. Zein is widely used in nano drug delivery systems due to its good biocompatibility. In this study, we prepared DM1-loaded zein nanoparticles (ZNPs) to ach...