Inhibition of cell proliferation by 2-fluorobenzaldehyde retinoic acid conjugate through suppression of STAT3 activation in human glioma cells

• Main Authors: Ji-Heng Hao (Author), Dian-Feng Hu (Author), Li-Mei Mao (Author), Shi-Gang Zhang (Author), Ji-Yue Wang (Author), Gang Li (Author)
• Format: Book
• Published: Bangladesh Pharmacological Society, 2015-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present study was performed to investigate the effect of 2-fluorobenzaldehyde retinoic acid conjugate on activation of STAT3 pathway in human glioma cells. The results revealed that the compound exhibited inhibitory effect on the activation of STAT3 induced constitutively and by interleukin-6. T...