IL-13 improves beta-cell survival and protects against IL-1beta-induced beta-cell death

• Main Authors: Sabine Rütti (Author), Cédric Howald (Author), Caroline Arous (Author), Emmanouil Dermitzakis (Author), Philippe A. Halban (Author), Karim Bouzakri (Author)
• Format: Book
• Published: Elsevier, 2016-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: IL-13 is a cytokine classically produced by anti-inflammatory T-helper-2 lymphocytes; it is decreased in the circulation of type 2 diabetic patients and impacts positively on liver and skeletal muscle. Although IL-13 can exert positive effects on beta-cell lines, its impact and mode of a...