The Na+/Ca2+ Exchanger 3 Is Functionally Coupled With the NaV1.6 Voltage-Gated Channel and Promotes an Endoplasmic Reticulum Ca2+ Refilling in a Transgenic Model of Alzheimer's Disease

• Príomhchruthaitheoirí: Ilaria Piccialli (Údar), Roselia Ciccone (Údar), Agnese Secondo (Údar), Francesca Boscia (Údar), Valentina Tedeschi (Údar), Valeria de Rosa (Údar), Pasquale Cepparulo (Údar), Lucio Annunziato (Údar), Anna Pannaccione (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

The remodelling of neuronal ionic homeostasis by altered channels and transporters is a critical feature of the Alzheimer's disease (AD) pathogenesis. Different reports converge on the concept that the Na+/Ca2+ exchanger (NCX), as one of the main regulators of Na+ and Ca2+ concentrations and si...