Downregulation of Candidate Gene Expression and Neuroprotection by Piperine in Streptozotocin-Induced Hyperglycemia and Memory Impairment in Rats

• Main Authors: Suresh Kumar (Author), Suman Chowdhury (Author), Ajay Razdan (Author), Deepa Kumari (Author), Ram Singh Purty (Author), Heera Ram (Author), Pramod Kumar (Author), Prasunpriya Nayak (Author), Sunil Dutt Shukla (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There is accumulating evidence showing that hyperglycemia conditions like diabetes possess a greater risk of impairment to the neuronal system because high glucose levels exacerbate oxidative stress, accumulation of amyloid-beta peptides, and mitochondrial dysfunction, and impair cognitive functions...