Estrogen and soy isoflavonoids decrease sensitivity of medulloblastoma and central nervous system primitive neuroectodermal tumor cells to chemotherapeutic cytotoxicity
Abstract Background Our previous studies demonstrated that growth and migration of medulloblastoma (MB), the most common malignant brain tumor in children, are stimulated by 17β-estradiol. The growth stimulating effects of estrogens are mediated through ERβ and insulin-like growth factor 1 signaling...
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| Main Authors: | , , , , , , |
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| Format: | Book |
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BMC,
2017-09-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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