Fingolimod and Diabetic Retinopathy: A Drug Repurposing Study

• Main Authors: Carlo Gesualdo (Author), Cornel Balta (Author), Chiara Bianca Maria Platania (Author), Maria Consiglia Trotta (Author), Hildegard Herman (Author), Sami Gharbia (Author), Marcel Rosu (Author), Francesco Petrillo (Author), Salvatore Giunta (Author), Alberto Della Corte (Author), Paolo Grieco (Author), Rosa Bellavita (Author), Francesca Simonelli (Author), Michele D'Amico (Author), Anca Hermenean (Author), Settimio Rossi (Author), Claudio Bucolo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study aimed to investigate the interactions between fingolimod, a sphingosine 1-phosphate receptor (S1PR) agonist, and melanocortin receptors 1 and 5 (MCR1, MCR5). In particular, we investigated the effects of fingolimod, a drug approved to treat relapsing-remitting multiple sclerosis, on retin...