Development of Liposomal Formulations of Zinc Diethyldithiocarbamate for Colorectal Cancer Treatment

• Main Authors: Niusha Ansari-Fard (Author), Ayse Kaya (Author), Dan Alves (Author), Basel Arafat (Author), Barbara Pierscionek (Author), Mohammad Najlah (Author)
• Format: Book
• Published: University of Huddersfield Press, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

(DDC)2Zn, disulfiram (DS) metabolite, has shown promising anticancer effects in vitro but further investigations in vivo are limited by its poor water solubility. In this study, liposomes are assessed as a delivery system for (DDC)2Zn. Liposomes were prepared by the thin-film hydration method, follo...