Topical Pirfenidone-Loaded Liposomes Ophthalmic Formulation Reduces Haze Development after Corneal Alkali Burn in Mice

• Main Authors: Carlos Daniel Diaz-Palomera (Author), Isaac Alejandro Vidal-Paredes (Author), Jose Navarro-Partida (Author), Margarita Cid-Hernandez (Author), Luis Carlos Rosales-Rivera (Author), Ricardo De la Rosa-Bibiano (Author), Hugo Christian Monroy-Ramirez (Author), Arturo Santos (Author), Juan Armendariz-Borunda (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Corneal chemical burns (CCBs) frequently result in corneal fibrosis or haze, an opacity of the cornea that obstructs vision and induces corneal blindness. Diverse strategies have been employed to prevent or reduce CCB-related corneal haze. In this study, we evaluated the physicochemical characterist...