African swine fever virus MGF505-3R inhibits cGAS-STING-mediated IFN-β pathway activation by degrading TBK1

• Main Authors: Mingyang Cheng (Author), Jiawei Luo (Author), Yuetong Duan (Author), Yu Yang (Author), Chunwei Shi (Author), Yu Sun (Author), Yiyuan Lu (Author), Junhong Wang (Author), Xiaoxu Li (Author), Jianzhong Wang (Author), Nan Wang (Author), Wentao Yang (Author), Yanlong Jiang (Author), Guilian Yang (Author), Yan Zeng (Author), Chunfeng Wang (Author), Xin Cao (Author)
• Format: Book
• Published: BMC, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract African swine fever virus (ASFV) is an important pathogen causing acute infectious disease in domestic pigs and wild boars that seriously endangers the global swine industry. As ASFV is structurally complex and encodes a large number of functional proteins, no effective vaccine has been dev...