Effect of polypharmacy on plasma bepridil concentration in patients with heart failure: a multicenter retrospective study

• Main Authors: Yuki Asai (Author), Hiroki Arihara (Author), Saki Omote (Author), Ena Tanio (Author), Saena Yamashita (Author), Takashi Higuchi (Author), Ei Hashimoto (Author), Momoko Yamada (Author), Hinako Tsuji (Author), Yoshihiro Kondo (Author), Makoto Hayashi (Author), Yoshiaki Yamamoto (Author)
• Format: Book
• Published: BMC, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Polypharmacy, defined as the concurrent use of over six drugs, is common in the treatment of heart failure (HF); however, unpredictable drug interactions with bepridil may occur. In this study, we have elucidated the influence of polypharmacy on plasma bepridil concentrations in...