MicroRNA-423-5p Promotes Autophagy in Cancer Cells and Is Increased in Serum From Hepatocarcinoma Patients Treated With Sorafenib

• Main Authors: Paola Stiuso (Author), Nicoletta Potenza (Author), Angela Lombardi (Author), Ida Ferrandino (Author), Antonio Monaco (Author), Silvia Zappavigna (Author), Daniela Vanacore (Author), Nicola Mosca (Author), Filomena Castiello (Author), Stefania Porto (Author), Raffaele Addeo (Author), Salvatore Del Prete (Author), Ferdinando De Vita (Author), Aniello Russo (Author), Michele Caraglia (Author)
• Format: Book
• Published: Elsevier, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hepatocellular carcinoma (HCC) is the third cause of cancer-related deaths worldwide. Sorafenib is the only approved drug for patients with advanced HCC but has shown limited activity. microRNAs (miRs) have been involved in several neoplasms including HCC suggesting their use or targeting as good to...