Succinic acid inhibits the activity of cytochrome P450 (CYP450) enzymes

• Main Authors: Hao Wang (Author), Bingyan Xia (Author), Mei Lin (Author), Yongpeng Wang (Author), Bin Sun (Author), Yuzhu Li (Author)
• Formato: Livro
• Publicado em: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Context Succinic acid, extracted from amber, is widely used in cardiovascular therapy. Objective The effect of succinic acid on the activity of cytochrome P450 (CYP450) enzymes was investigated in this study. Materials and methods The effect of succinic acid (100 μM) on the activity of eight isoform...