Genotypic status of the TbAT1/P2 adenosine transporter of Trypanosoma brucei gambiense isolates from Northwestern Uganda following melarsoprol withdrawal.
<h4>Background</h4>The development of arsenical and diamidine resistance in Trypanosoma brucei is associated with loss of drug uptake by the P2 purine transporter as a result of alterations in the corresponding T. brucei adenosine transporter 1 gene (TbAT1). Previously, specific TbAT1 mu...
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Main Authors: | Anne J N Kazibwe (Author), Barbara Nerima (Author), Harry P de Koning (Author), Pascal Mäser (Author), Michael P Barrett (Author), Enock Matovu (Author) |
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Format: | Book |
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Public Library of Science (PLoS),
2009-09-01T00:00:00Z.
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