Soft Coral-Derived Dihydrosinularin Exhibits Antiproliferative Effects Associated with Apoptosis and DNA Damage in Oral Cancer Cells

• Main Authors: Kun-Han Yang (Author), Yu-Sheng Lin (Author), Sheng-Chieh Wang (Author), Min-Yu Lee (Author), Jen-Yang Tang (Author), Fang-Rong Chang (Author), Ya-Ting Chuang (Author), Jyh-Horng Sheu (Author), Hsueh-Wei Chang (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dihydrosinularin (DHS) is an analog of soft coral-derived sinularin; however, the anticancer effects and mechanisms of DHS have seldom been reported. This investigation examined the antiproliferation ability and mechanisms of DHS on oral cancer cells. In a cell viability assay, DHS showed growth inh...