Induced neuronal activity does not attenuate amyloid beta‐induced synaptic loss in vitro

• Hauptverfasser: Rena Kono (Verfasst von), Gyu Li Kim (Verfasst von), Hidetaka Nagata (Verfasst von), Yuji Ikegaya (Verfasst von), Ryuta Koyama (Verfasst von)
• Format: Buch
• Veröffentlicht: Wiley, 2019-12-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Abstract Aim The accumulation of amyloid beta (Aβ) is one of the characteristics of Alzheimer's disease. The excessive accumulation of Aβ has been suggested to result in a decrease in the number of synapses. Although the number of synapses is generally modulated by neuronal activity, whether ne...