Action of Cyclooxygenase Inhibitors and a Leukotriene Biosynthesis Inhibitor on Cisplatin-Induced Acute and Delayed Emesis in the Ferret
Cisplatin at 5 mg/kg, i.p. induced an acute (day 1) and delayed (days 2 and 3) emetic response in the ferret that was used to investigate the anti-emetic activity of the non-selective cyclooxygenase inhibitor indomethacin (3 - 30 mg/kg, i.p., three times per day) and two cyclooxygenase-2 inhibitors,...
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Main Authors: | Tasia S.W. Sam (Author), Man P. Smith (Author), Denis Riendeau (Author), Annette Robichaud (Author), John A. Smith (Author) |
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Format: | Book |
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Elsevier,
2007-01-01T00:00:00Z.
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