Synthesis and Biological Evaluation of RGD-Cryptophycin Conjugates for Targeted Drug Delivery

Cryptophycins are potent tubulin polymerization inhibitors with picomolar antiproliferative potency in vitro and activity against multidrug-resistant (MDR) cancer cells. Because of neurotoxic side effects and limited efficacy in vivo, cryptophycin-52 failed as a clinical candidate in cancer treatmen...

Full description

Saved in:
Bibliographic Details
Main Authors: Adina Borbély (Author), Eduard Figueras (Author), Ana Martins (Author), Simone Esposito (Author), Giulio Auciello (Author), Edith Monteagudo (Author), Annalise Di Marco (Author), Vincenzo Summa (Author), Paola Cordella (Author), Raffaella Perego (Author), Isabell Kemker (Author), Marcel Frese (Author), Paola Gallinari (Author), Christian Steinkühler (Author), Norbert Sewald (Author)
Format: Book
Published: MDPI AG, 2019-04-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available