Effect of Blocking with Minicircle DNA of Interleukin-6 on Skin Allograft Rejection

• Main Authors: Doh Kyoung Chan (Author), Lim Sun Woo (Author), Jin Long (Author), Jin Jian (Author), Piao Shang Guo (Author), Chung Byung Ha (Author), Yang Chul Woo (Author)
• Format: Book
• Published: The Korean Society of Nephrology, 2014-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Blocking of proinflammatory cytokine, interleukin-6 (IL-6) is effective in decreasing resistance to allogenic tolerance. In this study, we investigated whether anti-IL-6 receptor producing nonviral minicircle (MC)-DNA, is competent to inhibit alloresponse-induced IL-6 in highly immunogenic murine sk...