Obesity worsens mitochondrial quality control and does not protect against skeletal muscle wasting in murine cancer cachexia

• Main Authors: Thomas D. Cardaci (Author), Brandon N. VanderVeen (Author), Brooke M. Bullard (Author), Sierra J. McDonald (Author), Christian A. Unger (Author), Reilly T. Enos (Author), Daping Fan (Author), Kandy T. Velázquez (Author), Norma Frizzell (Author), Espen E. Spangenburg (Author), E. Angela Murphy (Author)
• Format: Book
• Published: Wiley, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background More than 650 million people are obese (BMI > 30) worldwide, which increases their risk for several metabolic diseases and cancer. While cachexia and obesity are at opposite ends of the weight spectrum, leading many to suggest a protective effect of obesity against cachexia, m...