Gut Microbiota Participates in Antithyroid Drug Induced Liver Injury Through the Lipopolysaccharide Related Signaling Pathway

• Main Authors: Jiayu Sun (Author), Fuya Zhao (Author), Baiqiang Lin (Author), Jing Feng (Author), Xin Wu (Author), Yang Liu (Author), Lei Zhao (Author), Biqiang Zhu (Author), Yunwei Wei (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Drugs can alter the gut microbiota structure, and gut microbiota dysbiosis in turn is correlated with drug side effects through the intestinal endotoxemia hypothesis. Whether antithyroid drugs (including methimazole and propylthiouracil) cause gut microbiota dysbiosis and whether the gut...