Oleanolic Acid Acetate Alleviates Symptoms of Experimental Autoimmune Encephalomyelitis in Mice by Regulating Toll-Like Receptor 2 Signaling

• Main Authors: Minju Kim (Author), Soyoung Lee (Author), Hyungjin Lim (Author), Jihye Lee (Author), Ji-Young Park (Author), Hyung-Jun Kwon (Author), In-Chul Lee (Author), Young-Bae Ryu (Author), Jeongtae Kim (Author), Taekyun Shin (Author), Ginnae Ahn (Author), Mun-Chual Rho (Author), Kyungsook Jung (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Toll-like receptor 2 (TLR2) is expressed by several immune cells in the central nervous system and plays an important role in neuroinflammation. TLR2 upregulation has been reported in multiple sclerosis patients and in experimental autoimmune encephalomyelitis (EAE), a mouse model for multiple scler...