miR-133b Downregulation Reduces Vulnerable Plaque Formation in Mice with AS through Inhibiting Macrophage Immune Responses

• Main Authors: Cheng-Gen Zheng (Author), Bing-Yu Chen (Author), Ren-Hua Sun (Author), Xiao-Zhou Mou (Author), Fang Han (Author), Qian Li (Author), Hai-Jun Huang (Author), Jing-Quan Liu (Author), Yue-Xing Tu (Author)
• Format: Book
• Published: Elsevier, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Atherosclerosis (AS) is a chronic inflammatory disease characterized by accumulating deposition of lipids in the arterial intima. Notably, macrophages participate centrally in the pathogenesis of this deadly disease. In this study, we established AS mouse models in order to investigate the effect of...