IL-4Ralpha-independent expression of mannose receptor and Ym1 by macrophages depends on their IL-10 responsiveness.

IL-4Ralpha-independent expression of mannose receptor and Ym1 by macrophages depends on their IL-10 responsiveness.

IL-4Ralpha-dependent responses are essential for granuloma formation and host survival during acute schistosomiasis. Previously, we demonstrated that mice deficient for macrophage-specific IL-4Ralpha (LysM(cre)Il4ra(-/lox)) developed increased hepatotoxicity and gut inflammation; whereas inflammatio...

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Main Authors: Benjamin G Dewals (Author), Reece G Marillier (Author), Jennifer C Hoving (Author), Mosiuoa Leeto (Author), Anita Schwegmann (Author), Frank Brombacher (Author)
Format: Book
Published: Public Library of Science (PLoS), 2010-05-01T00:00:00Z.
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3rd Floor Main Library

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