IL-4Ralpha-independent expression of mannose receptor and Ym1 by macrophages depends on their IL-10 responsiveness.
IL-4Ralpha-dependent responses are essential for granuloma formation and host survival during acute schistosomiasis. Previously, we demonstrated that mice deficient for macrophage-specific IL-4Ralpha (LysM(cre)Il4ra(-/lox)) developed increased hepatotoxicity and gut inflammation; whereas inflammatio...
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Main Authors: | Benjamin G Dewals (Author), Reece G Marillier (Author), Jennifer C Hoving (Author), Mosiuoa Leeto (Author), Anita Schwegmann (Author), Frank Brombacher (Author) |
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Format: | Book |
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Public Library of Science (PLoS),
2010-05-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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