The cGAS-STING signaling in cardiovascular and metabolic diseases: Future novel target option for pharmacotherapy

• Main Authors: Patrick Kwabena Oduro (Author), Xianxian Zheng (Author), Jinna Wei (Author), Yanze Yang (Author), Yuefei Wang (Author), Han Zhang (Author), Erwei Liu (Author), Xiumei Gao (Author), Mei Du (Author), Qilong Wang (Author)
• Format: Book
• Published: Elsevier, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) signaling exert essential regulatory function in microbial-and onco-immunology through the induction of cytokines, primarily type I interferons. Recently, the aberrant and deranged signaling of the cGAS-STING axis is closely i...