G protein coupled receptor 41 regulates fibroblast activation in pulmonary fibrosis via Gαi/o and downstream Smad2/3 and ERK1/2 phosphorylation

• Principais autores: Zhengnan Ren (Autor), Xiaohua Pan (Autor), Jiahong Li (Autor), Xiaoliang Dong (Autor), Xing Tu (Autor), Li-Long Pan (Autor), Jia Sun (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2023-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Pulmonary fibrosis is a progressive and fatal fibrotic lung disease with mysterious pathogenesis and limited effective therapies. G protein-coupled receptors (GPRs) participate in a variety of physiologic functions, and several GPRs have critical fibrosis-promoting or -inhibiting roles in pulmonary...