G protein coupled receptor 41 regulates fibroblast activation in pulmonary fibrosis via Gαi/o and downstream Smad2/3 and ERK1/2 phosphorylation
Pulmonary fibrosis is a progressive and fatal fibrotic lung disease with mysterious pathogenesis and limited effective therapies. G protein-coupled receptors (GPRs) participate in a variety of physiologic functions, and several GPRs have critical fibrosis-promoting or -inhibiting roles in pulmonary...
Saved in:
Main Authors: | Zhengnan Ren (Author), Xiaohua Pan (Author), Jiahong Li (Author), Xiaoliang Dong (Author), Xing Tu (Author), Li-Long Pan (Author), Jia Sun (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2023-05-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
hucMSC-Ex Alleviates IBD-Associated Intestinal Fibrosis by Inhibiting ERK Phosphorylation in Intestinal Fibroblasts
by: Yifei Wang, et al.
Published: (2023) -
IL-6/JAK2-dependent G6PD phosphorylation promotes nucleotide synthesis and supports tumor growth
by: Xuemei Qiu, et al.
Published: (2023) -
G12R mutation in Cx26 downregulates the expression levels of TLR2 and its downstream inflammatory factors in keratinocytes
by: Zhaoying LIU, et al.
Published: (2023) -
G Protein-Coupled Estrogen Receptor 30 Reduces Transverse Aortic Constriction-Induced Myocardial Fibrosis in Aged Female Mice by Inhibiting the ERK1/2 -MMP-9 Signaling Pathway
by: Xiaowu Wang, et al.
Published: (2021) -
Participation of Gαi-Adenylate Cyclase and ERK1/2 in Mas Receptor Signaling Pathways
by: Valeria Burghi, et al.
Published: (2019)