HSP60 reduction protects against diet-induced obesity by modulating energy metabolism in adipose tissue

• Main Authors: Robert Hauffe (Author), Michaela Rath (Author), Mareike Schell (Author), Katrin Ritter (Author), Kai Kappert (Author), Stefanie Deubel (Author), Christiane Ott (Author), Markus Jähnert (Author), Wenke Jonas (Author), Annette Schürmann (Author), André Kleinridders (Author)
• Format: Book
• Published: Elsevier, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Insulin regulates mitochondrial function, thereby propagating an efficient metabolism. Conversely, diabetes and insulin resistance are linked to mitochondrial dysfunction with a decreased expression of the mitochondrial chaperone HSP60. The aim of this investigation was to determine the e...