Immunoglobulin replacement therapies in inborn errors of immunity: a review

• Main Authors: Archan Sil (Author), Suprit Basu (Author), Vibhu Joshi (Author), Rakesh Kumar Pilania (Author), Sangeetha Siniah (Author), Deepti Suri (Author), Amit Rawat (Author), Surjit Singh (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Immunoglobulins (Ig) were used as a therapeutic modality for the first time in a patient with X-linked agammaglobulinemia in 1952 by Colonel Ogden Bruton, decades before the molecular mechanisms causing the disease were unraveled. In many autoimmune and inflammatory illnesses, human immunoglobulin h...