Synthesis, characterization, and mechanistic insights into the enhanced anti-inflammatory activity of baicalin butyl ester via the PI3K-AKT pathway

• Main Authors: Hongxu Du (Author), Zhangxun Li (Author), Lijuan Su (Author), Zhengke He (Author), Xiaoyan Tan (Author), Fengzhi Hou (Author), Tanjie He (Author), Yu Pan (Author), Shuang Xu (Author), Liting Cao (Author), Shiqi Dong (Author), Yue Ma (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ObjectiveTo investigate the anti-inflammatory activity and mechanism of Baicalin derivative (Baicalin butyl ester, BE).MethodsBE was synthesized and identified using UV-Vis spectroscopy, FT-IR spectroscopy, mass spectrometry (MS) and high-performance liquid chromatography (HPLC) methods. Its anti-in...