Effect of Rho-Kinase and Autophagy on Remote Ischemic Conditioning-Induced Cardioprotection in Rat Myocardial Ischemia/Reperfusion Injury Model

• Main Authors: Jie Gao (Author), Feng Min (Author), Shasha Wang (Author), Heng Lv (Author), Huan Liang (Author), Ben Cai (Author), Xianjie Jia (Author), Qin Gao (Author), Ying Yu (Author)
• Format: Book
• Published: Hindawi-Wiley, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective. Remote ischemic conditioning (RIC) is a cardioprotective method in ischemia/reperfusion (I/R) injury. This study investigated the mechanism of Rho-kinase-mediated autophagy in RIC. Methods. Sixty male Sprague-Dawley rats were randomly divided into six groups: sham, I/R, RIC, I/R+fasudil,...