Pharmacological Vitamin C Treatment Impedes the Growth of Endogenous Glutamine-Dependent Cancers by Targeting Glutamine Synthetase
Purpose: Glutamine synthetase (GS) is the only currently known enzyme responsible for synthesizing endogenous glutamine (Gln). GS exerts a critical role in the oncogenesis of endogenous Gln-dependent cancers, making it an attractive target for anti-tumor therapies. A mixed-function oxidation system...
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Main Authors: | Yali Long (Author), Jia Qiu (Author), Bing Zhang (Author), Peng He (Author), Xinchong Shi (Author), Qiao He (Author), Zhifeng Chen (Author), Wanqing Shen (Author), Zhoulei Li (Author), Xiangsong Zhang (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2021-05-01T00:00:00Z.
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