Stepwise Glucoheptoamidation of Poly(Amidoamine) Dendrimer G3 to Tune Physicochemical Properties of the Potential Drug Carrier: In Vitro Tests for Cytisine Conjugates

• Main Authors: Anna Czerniecka-Kubicka (Author), Piotr Tutka (Author), Marek Pyda (Author), Małgorzata Walczak (Author), Łukasz Uram (Author), Maria Misiorek (Author), Ewelina Chmiel (Author), Stanisław Wołowiec (Author)
• Format: Book
• Published: MDPI AG, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Third-generation poly(amidoamine) dendrimer (PAMAM) was modified by stepwise primary amine group amidation with <span style="font-variant: small-caps;">d</span>-glucoheptono-1,4-lactone. The physicochemical properties of the conjugates-size, ζ potential in lysosomal pH 5 and in...