Pharmacokinetic of Diclofenac in the Presence and Absence of Glibenclamide in the Rat

• Główni autorzy: María R. León-Reyes (Autor), Gilberto Castañeda-Hernández (Autor), Mario I Ortiz (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2009-10-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

ABSTRACT - PURPOSE. There is evidence that the sulfonylurea antidiabetic agent glibenclamide reduces the analgesic action of non-steroidal anti-inflammatory drugs (NSAIDs), opioids and neuromodulators in animal models. Therefore, in view of the vast clinical uses and interactions of NSAIDs with comm...